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产品信息
310-16-20UG
产品规格
种属
Human
已发表种属
Human
Expression System
E. coli
氨基酸序列
AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
分子量
5.3 kDa
分类
Recombinant
类型
Protein
纯度
≥ 98% by SDS-PAGE gel and HPLC analyses.
内毒素浓度
<1 EU/µg
活性
Determined by its ability to neutralize APRIL-induced NF-κB activation in HEK293-NF-κB reporter cells transfected with BCMA receptor.
偶联物
形式
Lyophilized
纯化类型
purified
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
产品详细信息
Recombinant soluble Human BCMA is a 50 amino acid polypeptide (5.3 kDa) comprising the TNFR homologous region of the BCMA protein.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
靶标信息
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: B cell maturation antigen; B-cell maturation factor; B-cell maturation protein; CD269; Tumor necrosis factor receptor superfamily member 17; tumor necrosis factor receptor superfamily, member 17
基因别名: BCM; BCMA; CD269; TNFRSF13A; TNFRSF17
UniProt ID: (Human) Q02223
Entrez Gene ID: (Human) 608
