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Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61393. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Bruno -like 6, RNA binding protein; bruno-like 6, RNA binding protein; Bruno-like protein 6; CELF-6; CUG-BP and ETR-3 like factor 6; CUG-BP- and ETR-3-like factor 6; CUGBP Elav-like family member 6; RNA-binding protein BRUNOL-6
基因别名: BRUNOL6; CELF6
UniProt ID: (Human) Q96J87
Entrez Gene ID: (Human) 60677