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Highest antigen sequence indentity to the following orthologs: Mouse (39%), Rat (39%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63587. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Bestrophin-4; vitelliform macular dystrophy 2-like 2; Vitelliform macular dystrophy 2-like protein 2
基因别名: BEST4; VMD2L2
UniProt ID: (Human) Q8NFU0
Entrez Gene ID: (Human) 266675