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Highest antigen sequence indentity to the following orthologs: Mouse (70%), Rat (70%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84127. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for a distribution of the CatSper complex in linear quadrilateral nanodomains along the flagellum, maximizing fertilization inside the mammalian female reproductive tract. Together with EFCAB9, associates with the CatSper channel pore and is required for the two-row structure of each single CatSper channel. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cation channel sperm-associated auxiliary subunit zeta; CatSper-zeta; Testis-expressed protein 40
基因别名: C11orf20; CATSPERZ; TEX40
UniProt ID: (Human) Q9NTU4
Entrez Gene ID: (Human) 25858