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Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55561. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Is required for meiosis completion in both male and female germ cells. Confers stability to numerous meiotic mRNAs in gonads allowing proper initiation and progression into meiosis prophase I. The function may involve YTHDC2 and is independent of induction by retinoic acid (RA). Maintains an extended meiotic prophase I by properly promoting the transition from a mitotic to a meiotic cell cycle program by binding transcripts through its interaction with YTHDC2 that regulate the mitotic cell cycle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Meiosis-specific coiled-coil domain-containing protein MEIOC; Meiosis-specific with coiled-coil domain protein; uncharacterized protein C17orf104
基因别名: C17orf104; MEIOC
UniProt ID: (Human) A2RUB1
Entrez Gene ID: (Human) 284071