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Highest antigen sequence indentity to the following orthologs: Mouse (68%), Rat (68%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66690. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation (PubMed:22854966). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:29332244). Involved in cell migration. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Angiotonin-transactivated protein 1; Elongator complex protein 6; elongator complex protein 6 homolog; Protein TMEM103; transmembrane protein 103; UPF0405 protein C3orf75
基因别名: ATP1; C3orf75; ELP6; TMEM103
UniProt ID: (Human) Q0PNE2
Entrez Gene ID: (Human) 54859