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Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54196. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATP/GTP binding protein-like 3; ATP/GTP-binding protein-like 3; CBCP3; Cytosolic carboxypeptidase 3; Protein deglutamylase CCP3
基因别名: AGBL3; CCP3
UniProt ID: (Human) Q8NEM8
Entrez Gene ID: (Human) 340351