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Highest antigen sequence indentity to the following orthologs: Mouse (47%), Rat (47%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-64421. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
CEACAM7 is a CEA-related cell adhesion molecule 7 that belongs to the carcinoembryonic antigen (CEA) family. CEACAM7 encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein which is only found on the apical surface of highly differentiated epithelial cells adult colon and on a small epithelial cell population in pancreatic ducts. CEACAM7 expression is completely lost upon malignant transformation already in hyperplastic polyps and early adenomas as well as in adenocarcinomas of the colon. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constant-like A domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BGP; BGP7; Carcinoembryonic antigen CGM2; carcinoembryonic antigen gene family member 2; Carcinoembryonic antigen-related cell adhesion molecule 7; CEA; CEA cell adhesion molecule 7
基因别名: CEACAM7; CGM2
UniProt ID: (Human) Q14002
Entrez Gene ID: (Human) 1087