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Highest antigen sequence indentity to the following orthologs: Mouse (71%), Rat (71%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54796. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Plays a role in mitotic exit and cytokinesis (PubMed:16198290, PubMed:17853893). Recruits PDCD6IP and TSG101 to midbody during cytokinesis. Required for successful completion of cytokinesis (PubMed:17853893). Not required for microtubule nucleation (PubMed:16198290). Plays a role in the development of the brain and kidney (PubMed:28264986). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cancer/testis antigen 111; centrosomal protein 55kDa; Centrosomal protein of 55 kDa; Cep55; Up-regulated in colon cancer 6
基因别名: C10orf3; CEP55; CT111; URCC6
UniProt ID: (Human) Q53EZ4
Entrez Gene ID: (Human) 55165