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Highest antigen sequence indentity to the following orthologs: Mouse (66%), Rat (66%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82645. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Carboxylesterase 2; carboxylesterase 2 (intestine, liver); CE-2; CES-2; Cocaine esterase; hCE-2; intestinal carboxylesterase; liver carboxylesterase-2; Methylumbelliferyl-acetate deacetylase 2; P iCE
基因别名: CE-2; CES2; CES2A1; ICE; PCE-2
UniProt ID: (Human) O00748
Entrez Gene ID: (Human) 8824