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Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52892. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATP-dependent helicase CHD4; CHD-4; Chromodomain-helicase-DNA-binding protein 4; Mi-2 autoantigen 218 kDa protein; Mi2-beta; MI2B
基因别名: CHD-4; CHD4; Mi-2b; Mi2-BETA
UniProt ID: (Human) Q14839
Entrez Gene ID: (Human) 1108