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Highest antigen sequence indentity to the following orthologs: Mouse (74%), Rat (74%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-139944. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
CHRDL2 encodes a member of the chordin family of proteins. Chordin family members are secreted proteins that share a cysteine-rich pro-collagen repeat domain and associate with members of the transforming growth factor beta superfamily. In vitro assays demonstrate a direct interaction between the encoded protein and human activin A. This gene is expressed in many tissues including osteoblasts, where it is differentially expressed during differentiation. In addition, its expression is upregulated in human osteoarthritic joint cartilage, suggesting a role in adult cartilage regeneration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BNF-1; Breast tumor novel factor 1; chordin-like 2; Chordin-like protein 2; Chordin-related protein 2; FKSG37
基因别名: BNF1; CHL2; CHRDL2; UNQ765/PRO1557
UniProt ID: (Human) Q6WN34
Entrez Gene ID: (Human) 25884