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Highest antigen sequence indentity to the following orthologs: Mouse (54%), Rat (54%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-144825. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
After binding acetylcholine, the ACHR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: acetylcholine receptor; acetylcholine receptor, nicotinic, alpha 2 (neuronal); cholinergic receptor; cholinergic receptor, nicotinic alpha 2; cholinergic receptor, nicotinic, alpha 2 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal); Neuronal acetylcholine receptor subunit alpha-2
基因别名: CHRNA2
UniProt ID: (Human) Q15822
Entrez Gene ID: (Human) 1135