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产品信息
RP-90924
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
DPEHAKPESSEAPSGNLKQPETAAALASSGSVD
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (42%), Rat (42%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53089. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Chemokines are members of a superfamily of small inducible, secreted, pro-inflammatory cytokines. Members of the chemokine-like factor superfamily (CKLFSF) share similarities with both chemokine and transmembrane 4 superfamilies of signaling molecules. As a member of the CKLFSF family of proteins, CMTM1 (CKLF-like MARVEL transmembrane domain-containing protein 1), also known as CKLFSF1 (Chemokine-like factor superfamily member 1), is a 169 amino acid multi-pass membrane protein that is highly expressed in testis, therefore probably playing a role in spermatogenesis or testicular development. CMTM1 contains a CC-chemokine motif and four transmembrane segments. The gene encoding CMTM1 resides in a tight gene cluster on human chromosome 16 with CKLF, CMTM2, CMTM3 and CMTM4. There are at least sixteen isoforms of CMTM1 that are produced as a result of alternative splicing events.
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生物信息学
蛋白别名: chemokine-like factor super family 1; chemokine-like factor superfamily 1; Chemokine-like factor superfamily member 1; chemokine-like factor-like protein CKLFH1; CKLF-like MARVEL transmembrane domain containing 1; CKLF-like MARVEL transmembrane domain-containing protein 1
基因别名: CKLFH; CKLFH1; CKLFSF1; CMTM1
UniProt ID: (Human) Q8IZ96
Entrez Gene ID: (Human) 113540
