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Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83620. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
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蛋白别名: cardiac LIM domain protein; Cardiac LIM protein; CRP3; Cysteine and glycine-rich protein 3; cysteine and glycine-rich protein 3 (cardiac LIM protein); Cysteine-rich protein 3; LIM domain only 4; LIM domain protein, cardiac; MGC14488; MGC61993; Muscle LIM protein; muscle lim protein isoform
基因别名: CLP; CMD1M; CMH12; CRP3; CSRP3; LMO4; MLP
UniProt ID: (Human) P50461
Entrez Gene ID: (Human) 8048