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产品信息
PHG0286
应用
建议稀释比
已发表文章
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
GKKCIRTPKI SKPIKFELSG CTSMKTYRAK FCGVCTDGRC CTPHRTTTLP VEFKCPDGEV MKKNMMFIKT CACHYNCPGD NDIFESLYYR KMYGDMA
分子量
11.2 kDa
分类
Recombinant
类型
Protein
纯度
≥95% by SDS-PAGE and HPLC
内毒素浓度
<0.1 ng/µg
活性
ED50 = 1 - 2 µg/mL; determined by the dose-dependent proliferation of HUVECs.
偶联物
形式
Lyophilized
纯化类型
purified
保存液
10mM sodium acetate, pH 6
内含物
no preservative
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile, distilled water, to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2°C to 8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein, such as 0.1% BSA and store in working aliquots at -20°C to -80°C.
Storage: The lyophilized protein is stable at room temperature for 1 month, but should be kept at -20°C for long term storage, preferably desiccated. Working aliquots stored with a carrier protein are stable for at least 10 months at -20°C to -80°C. Avoid repeated freeze/thaw cycles.
靶标信息
Connective Tissue Growth Factor (CTGF), also called CCN2, is a member of the CCN family. CTGF is a secreted protein produced by umbilical veins and vascular endothelial cells. CTGF possesses an Insulin-like Growth Factor (IGF)-binding domain, a thrombospondin type 1 domain, and a cysteine knot region. CTGF plays important roles in the proliferation and differentiation of chondrocytes, induces angiogenesis, and promotes cell adhesion in fibroblasts, endothelial, and epithelial cells.
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生物信息学
蛋白别名: 2-Nov; CCN family member 2; Cellular communication network factor 2; Connective tissue growth factor; H-CTGF; Hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; Insulin-like growth factor-binding protein 8; MGC102839
基因别名: CCN2; CTGF; HCS24; IGFBP8; NOV2
UniProt ID: (Human) P29279
Entrez Gene ID: (Human) 1490
