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Highest antigen sequence indentity to the following orthologs: Mouse (81%), Rat (81%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67316. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta- subunit of coatomer complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Calpain-8; nCL-2; New calpain 2; Stomach-specific M-type calpain
基因别名: CAPN8; nCL-2; NCL2
UniProt ID: (Human) A6NHC0
Entrez Gene ID: (Human) 388743