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Highest antigen sequence indentity to the following orthologs: Mouse (91%), Rat (91%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54705. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
DDHD2, also known as KIAA0725p, is a member of the intracellular phospholipase A1 (PLA1) protein family which comprises a group of enzymes that hydrolyze the sn-1 ester bond of phospholipids, producing 2-acyl-lysophospholipids and fatty acids. DDHD2 prefers phosphatidic acid as substrate and has a role in efficient membrane trafficking from the Golgi apparatus to the plasma membrane. The gene of DDHD2 maps to chromosome 8p11.23, and encodes a 711-amino-acid protein with a calculated molecular mass of 81 kDa. It has been reported that DDHD2 immunoblot analysis of various tissue extracts revealed two bands of 90 and 85 kDa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DDHD domain-containing protein 2; intracellular phospholipase A1gamma; KIAA0725p; PA-PLA1 like; Phospholipase DDHD2; SAM, WWE and DDHD domain-containing protein 1; sec23p-interacting protein p125-like phosphatidic acid-preferring phospholipase A1
基因别名: DDHD2; iPLA(1)gamma; KIAA0725; SAMWD1; SPG54
UniProt ID: (Human) O94830
Entrez Gene ID: (Human) 23259