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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66083. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; DEAD box protein 46; Probable ATP-dependent RNA helicase DDX46; PRP5 homolog; Prp5-like DEAD-box protein; RNA helicase
基因别名: DDX46; KIAA0801; Prp5; PRPF5
UniProt ID: (Human) Q7L014
Entrez Gene ID: (Human) 9879