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Highest antigen sequence indentity to the following orthologs: Mouse (74%), Rat (74%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59661. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 80 kDa diacylglycerol kinase; DAG kinase alpha; DGK-alpha; Diacylglycerol kinase alpha; diacylglycerol kinase, alpha 80kDa; Diglyceride kinase; Diglyceride kinase alpha; MGC12821; MGC42356
基因别名: DAGK; DAGK1; DGK-alpha; DGKA
UniProt ID: (Human) P23743
Entrez Gene ID: (Human) 1606