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Highest antigen sequence indentity to the following orthologs: Mouse (66%), Rat (66%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84732. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 from CML cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Docking protein 2; docking protein 2, 56kD; docking protein 2, 56kDa; Downstream of tyrosine kinase 2; p56(dok-2)
基因别名: DOK2; p56DOK; p56dok-2
UniProt ID: (Human) O60496
Entrez Gene ID: (Human) 9046