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Highest antigen sequence indentity to the following orthologs: Mouse (73%), Rat (73%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53004. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The desmosomal cadherin desmocollin DSC1 is expressed in upper epidermis where strong adhesion is required. DSC1 is a type I membrane protein (4) required for strong adhesion and barrier maintenance in epidermis and contributes to epidermal differentiation.The DSC1 gene comprises 17 exons spanning approximately 33 kb on 18q12.1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cadherin family member 1; Desmocollin-1; Desmocollin1; Desmosomal glycoprotein 2/3; DG2/DG3
基因别名: CDHF1; DG2/DG3; DSC1
UniProt ID: (Human) Q08554
Entrez Gene ID: (Human) 1823