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Highest antigen sequence indentity to the following orthologs: Mouse (91%), Rat (91%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54747. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Down syndrome critical region 3; Down syndrome critical region gene 3; Down syndrome critical region protein 3; Down syndrome critical region protein A; Vacuolar protein sorting-associated protein 26C
基因别名: DCRA; DSCR3; DSCRA; VPS26C
UniProt ID: (Human) O14972
Entrez Gene ID: (Human) 10311