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产品信息
RP-99405
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
SVTVGGEQISAIGRGICVLLGISLEDTQKELEHMVRKILNLRVFEDESGKHWSKSVMDKQYEILCVSQFT
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
Unconjugated
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59376. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis. It is a holoenzyme shell (approximately 450 kDa) consisting of 24 subunits of two types, H (heavy) and L (light), and capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiologic status of the cell, the ratio of H to L subunits in ferritin can vary widely. It can be viewed not only as part of a group of iron regulatory proteins that include transferrin and the transferrin receptor, but also as a member of the protein family that orchestrates the cellular defense against stress and inflammation. Ferritin is found in the liver, spleen, kidney and heart. Only a small amount is found in the blood. The blood level of ferritin serves as an indicator of the amount of iron stored in the body.
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生物信息学
蛋白别名: bA379J5.3; bA555E18.1; D-aminoacyl-tRNA deacylase 1; D-tyrosyl-tRNA deacylase 1 homolog; DNA-unwinding element-binding protein B; DTD; DUE-B; Gly-tRNA(Ala) deacylase; Histidyl-tRNA synthase-related; histidyl-tRNA synthetase 2; MGC119131; MGC41905
基因别名: C20orf88; DTD1; DUE-B; DUEB; HARS2; pqn-68
UniProt ID: (Human) Q8TEA8
Entrez Gene ID: (Human) 92675
