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Highest antigen sequence indentity to the following orthologs: Mouse (39%), Rat (39%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibodies, PA5-139755, PA5-82540. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: defensin 5; Defensin alpha 5; defensin, alpha 5, Paneth cell-specific; defensin, alpha 5, preproprotein; Defensin-5; HD5; HD5(20-94); MGC129728
基因别名: DEF5; DEFA5; HD-5
UniProt ID: (Human) Q01523
Entrez Gene ID: (Human) 1670