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Highest antigen sequence indentity to the following orthologs: Mouse (56%), Rat (56%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51559. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: epididymal secretory protein E3 beta; Epididymal secretory protein E3-beta; family with sequence similarity 12, member B (epididymal); HE3-beta; human epididymis-specific 3 beta; Human epididymis-specific protein 3-beta; ribonuclease A M2
基因别名: EDDM3B; EP3B; FAM12B; HE3-BETA; HE3B; RAM2; UNQ6412/PRO21187
UniProt ID: (Human) P56851
Entrez Gene ID: (Human) 64184