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Highest antigen sequence indentity to the following orthologs: Mouse (77%), Rat (77%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51602. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cas scaffolding protein family member 3; Embryonal Fyn-associated substrate; hEFS; signal transduction protein (SH3 containing)
基因别名: CAS3; CASS3; EFS; EFS1; EFS2; HEFS; SIN
UniProt ID: (Human) O43281
Entrez Gene ID: (Human) 10278