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Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Endo G; Endonuclease G, mitochondrial; mitochondrial endonuclease G
基因别名: ENDOG
UniProt ID: (Human) Q14249
Entrez Gene ID: (Human) 2021