Search Thermo Fisher Scientific
Highest antigen sequence indentity to the following orthologs: Mouse (36%), Rat (36%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56955. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex class I molecules rely on aminopeptidases such as ERAP1 and LRAP to trim precursors to antigenic peptides in the endoplasmic reticulum following cleavage in the cytoplasm by tripeptidyl peptidase II.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Endoplasmic reticulum aminopeptidase 2; FLJ23633; FLJ23701; FLJ23807; L-RAP; Leukocyte-derived arginine aminopeptidase
基因别名: ERAP2; L-RAP; LRAP
UniProt ID: (Human) Q6P179
Entrez Gene ID: (Human) 64167