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Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp686F03189; ERK-3; Extracellular signal-regulated kinase 3; extracellular signal-regulated kinase, p97; MAP kinase 6; MAP kinase isoform p97; MAPK 6; Mitogen-activated protein kinase 6; p97-MAPK; protein kinase, mitogen-activated 5; protein kinase, mitogen-activated 6
基因别名: ERK3; HsT17250; MAPK6; p97MAPK; PRKM6
UniProt ID: (Human) Q16659
Entrez Gene ID: (Human) 5597