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Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-110629. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Endoplasmic reticulum resident protein 44; endoplasmic reticulum resident protein 44 kDa; ER protein 44; OTTHUMP00000063799; protein disulfide isomerase family A, member 10; thioredoxin domain containing 4 (endoplasmic reticulum); Thioredoxin domain-containing protein 4
基因别名: ERP44; KIAA0573; PDIA10; TXNDC4; UNQ532/PRO1075
UniProt ID: (Human) Q9BS26
Entrez Gene ID: (Human) 23071