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Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58360. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 3'-5' exoribonuclease CSL4 homolog; exosomal core protein CSL4; Exosome complex component CSL4; Exosome component 1; hCsl4p; homolog of yeast exosomal core protein CSL4; RP11-452K12.9
基因别名: CGI-108; CSL4; Csl4p; EXOSC1; p13; SKI4; Ski4p
UniProt ID: (Human) Q9Y3B2
Entrez Gene ID: (Human) 51013