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产品信息
300-48-20UG
应用
建议稀释比
已发表文章
产品规格
种属
Human
已发表种属
Bacteria,
Human,
Mouse
Expression System
E. coli
氨基酸序列
TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L
分子量
8.4 kDa
分类
Recombinant
类型
Protein
纯度
≥ 98% by SDS-PAGE gel and HPLC analyses.
内毒素浓度
<1 EU/µg
活性
Determined by its ability to chemoattract human CCR3/HEK293 cells. The maximum activity was achieved at 2ug/ml.
偶联物
形式
Lyophilized
纯化类型
purified
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
产品详细信息
Recombinant Human Eotaxin-3 is an 8.4 kDa protein containing 71 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
靶标信息
Eotaxin-3 is a small cytokine belonging to the CC chemokine family that is also called CCL26, Chemokine (C-C motif) ligand 26. Chemokines play pivotal roles in health and disease by controlling migration and tissue localization of specific types of cells expressing their cognate receptors. Eotaxin-3 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4. This gene for chemokine is located on human chromosome 7. Eotaxin-3 induced migration of eosinophils and basophils only at a 10-fold higher concentration than eotaxin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: C-C motif chemokine 26; CC chemokine IMAC; chemokine (C-C motif) ligand 26; chemokine N1; Eotaxin-3; Eotaxin3; Macrophage inflammatory protein 4-alpha; MGC126714; MIP-4-alpha; PRO242; SCYA26MIP-4-alpha; small inducible cytokine A26; small inducible cytokine subfamily A (Cys-Cys), member 26; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1; UNQ216
基因别名: CCL26; IMAC; MIP-4a; MIP-4alpha; SCYA26; TSC-1; UNQ216/PRO242
UniProt ID: (Human) Q9Y258
Entrez Gene ID: (Human) 10344
