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Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EPB6; EphB6v; Epherin B6; Epherin receptor B6; Ephrin type-B receptor 6; HEP; human kinase-defective Eph-family receptor protein; MGC129910; MGC129911; Tyrosine-protein kinase-defective receptor EPH-6
基因别名: EPHB6; HEP
UniProt ID: (Human) O15197
Entrez Gene ID: (Human) 2051