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产品信息
RP-94701
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
DTEILKVARTHHVQAESYLVYNIMSSGEIECSNTLEDELDQALPSQAFIYRPIRQRVYSLLLEDCQDVTSTCLAVKEWFVYPGNPL
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (80%), Rat (80%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57984. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The transcription factor peroxisome proliferator-activated receptor -gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.
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生物信息学
蛋白别名: Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Constitutive coactivator of PPAR-gamma; f120b; PGCC1; PPARG constitutive coactivator 1; PPARgamma constitutive coactivator 1; Protein FAM120B
基因别名: CCPG; dJ894D12.1; FAM120B; KIAA1838; PGCC1
UniProt ID: (Human) Q96EK7
Entrez Gene ID: (Human) 84498
