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Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65635. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene is located near the gene for the lysosomal enzyme glucosylceramidase; a deficiency in this enzyme is associated with Gaucher disease. The encoded protein has been identified as a potential binding partner of a WW domain-containing protein which is involved in apoptosis and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Endosomal transmembrane epsin interactor 3; family with sequence similarity 189, member B; Protein COTE1; Protein ENTREP3
基因别名: C1orf2; COTE1; ENTREP3; FAM189B
UniProt ID: (Human) P81408
Entrez Gene ID: (Human) 10712