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产品信息
RP-105814
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
AELIPDAPLSSAAYSIRSIGERPVLKAPV
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65050. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events.
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生物信息学
蛋白别名: 21-Feb; Cytokine-like protein 2-21; D21M16SJHU19e; family with sequence similarity 3, member B; pancreatic derived factor; Pancreatic-derived factor; PANDER; Protein FAM3B
基因别名: 2-21; C21orf11; C21orf76; FAM3B; ORF9; PANDER; PRED44; UNQ320/PRO365
UniProt ID: (Human) P58499
Entrez Gene ID: (Human) 54097
