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This peptide corresponds to 19 amino acids near the carboxy terminus of human FAM59B.
PEP-0960 can be used as a blocking peptide with polyclonal antibody PA5-20846.
FAM59B is related to the FAM59A protein (also known as GAREM). While little is known of the role of the FAM59B protein, FAM59A is a downstream molecule in the EGF signaling pathway and binds Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. Like FAM59A, FAM59B may play a role in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: family with sequence similarity 59, member B; GRB2 associated regulator of MAPK1 2; GRB2 associated, regulator of MAPK1-like; GRB2-associated and regulator of MAPK protein 2; GRB2-associated and regulator of MAPK protein-like; GRB2-associated and regulator of MAPK1-like; protein FAM59B
基因别名: FAM59B; GAREM2; GAREML; HRIHFB2063; KIAA2038
UniProt ID: (Human) Q75VX8
Entrez Gene ID: (Human) 150946