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Highest antigen sequence indentity to the following orthologs: Mouse (45%), Rat (45%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56989. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BJ-HCC-2 antigen; Cancer/testis antigen 43; CT43; fetal and adult testis expressed transcript protein; Fetal and adult testis-expressed transcript protein; Tumor antigen BJ-HCC-2
基因别名: CT43; FATE; FATE1
UniProt ID: (Human) Q969F0
Entrez Gene ID: (Human) 89885