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Highest antigen sequence indentity to the following orthologs: Mouse (58%), Rat (58%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56074. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5- bisphosphate, phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4- monophosphate and phosphatidylinositol 3-monophosphate.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FGD1 family, member 2; FLJ00276 protein; FYVE, RhoGEF and PH domain-containing protein 2; Zinc finger FYVE domain-containing protein 4
基因别名: FGD2; ZFYVE4
UniProt ID: (Human) Q7Z6J4
Entrez Gene ID: (Human) 221472