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产品信息
RP-88925
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
LPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGT
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51470. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 25 kDa FK506-binding protein; 25 kDa FKBP; FK506 binding protein 3, 25kDa; FK506-binding protein 25, T-cell; FK506-binding protein 3; FK506-binding protein 3 (25kD); FKBP-3; Immunophilin FKBP25; Peptidyl-prolyl cis-trans isomerase FKBP3; PPIase FKBP3; rapamycin binding protein; Rapamycin-selective 25 kDa immunophilin; Rotamase
基因别名: FKBP-25; FKBP-3; FKBP25; FKBP3; PPIase
UniProt ID: (Human) Q00688
Entrez Gene ID: (Human) 2287
