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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51720. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
FMNL3, also known as Formin-like protein 3, is a 1028 amino acid containing protein involved in immunity or defense. This developmental protein is implicated in polarity control, invasion, migration, or metastasis through regulation of the Rho-related signaling pathway. It belongs to the formin homology family and contains a FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain and has high sequence identity to the mouse Wbp3 protein. Two different isoforms have been described. Itis suspectedbe involved in gastric cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Formin homology 2 domain-containing protein 3; formin-like 3; Formin-like protein 3; WBP-3; WW domain binding protein 3; WW domain-binding protein 3
基因别名: FHOD3; FMNL3; FRL2; KIAA2014; WBP-3; WBP3
UniProt ID: (Human) Q8IVF7
Entrez Gene ID: (Human) 91010