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Highest antigen sequence indentity to the following orthologs: Mouse (67%), Rat (67%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84248. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq, Oct 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FRAT-1; Frequently rearranged in advanced T-cell lymphomas 1; Proto-oncogene FRAT1
基因别名: FRAT1
UniProt ID: (Human) Q92837
Entrez Gene ID: (Human) 10023