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Highest antigen sequence indentity to the following orthologs: Mouse (64%), Rat (64%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-144723. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp761B039; HD10; Histone deacetylase 10; MGC149722; Polyamine deacetylase HDAC10; RP3-402G11.7
基因别名: HD10; HDAC10
UniProt ID: (Human) Q969S8
Entrez Gene ID: (Human) 83933