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Highest antigen sequence indentity to the following orthologs: Mouse (58%), Rat (58%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54037. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
HEMGN regulates the proliferation and differentiation of hematopoietic cells. Overexpression of HEMGN block the TPA-induced megakaryocytic differentiation in the K562 cell model. HEMGN may also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EDAG-1; Erythroid differentiation-associated gene protein; Hemogen; Hemopoietic gene protein; Negative differentiation regulator protein
基因别名: CT155; EDAG; EDAG-1; HEMGN; NDR; PRO1037; PRO1620
UniProt ID: (Human) Q9BXL5
Entrez Gene ID: (Human) 55363