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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60199. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: H2B histone family, member Q; H2B-clustered histone 21; H2B/q; histone 2, H2be; Histone H2B type 2-E; Histone H2B-GL105; Histone H2B.q; Histone H2Bq
基因别名: GL105; H2B; H2B.1; H2BC21; H2BFQ; H2BGL105; H2BQ; HIST2H2BE
UniProt ID: (Human) Q16778
Entrez Gene ID: (Human) 8349