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Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-140137. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factorm HOXA10, that may regulate gene expression, morphogenesis, and differentiation. More specifically, HOXA10 may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: homeo box A10; homeobox protein 1H; Homeobox protein Hox-1.8; Homeobox protein Hox-1H; Homeobox protein Hox-A10; homeobox protein HOXA10; Hox-18; PL
基因别名: HOX1; HOX1.8; HOX1H; HOXA10; PL
UniProt ID: (Human) P31260
Entrez Gene ID: (Human) 3206