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Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66661. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
HOXD13 (homeobox protein D13) belongs to a class of transcription factors called homeobox proteins. In vertebrates, homeobox are found in clusters called A, B, C, and D on four separate chromosomes. Expression of homeobox proteins is spatially and temporally regulated during embryonic development. The gene encoding HOXD13 is part of the D cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in the HOXD13 gene cause synpolydactyly.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: homeo box 4I; homeo box D13; Homeobox protein Hox-4I; Homeobox protein Hox-D13
基因别名: BDE; BDSD; HOX4I; HOXD13; SPD; SPD1
UniProt ID: (Human) P35453
Entrez Gene ID: (Human) 3239