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Highest antigen sequence indentity to the following orthologs: Mouse (74%), Rat (74%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65521. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AT-HSFB1; ATHSF4; cataract; Heat shock factor protein 4; Heat shock transcription factor 4; hHSF4; HSF 4; HSFB1; HSTF 4; Marner
基因别名: CTM; CTRCT5; HSF4
UniProt ID: (Human) Q9ULV5
Entrez Gene ID: (Human) 3299