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Highest antigen sequence indentity to the following orthologs: Mouse (79%), Rat (79%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51393. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 17S U2 SnRNP complex component HTATSF1; cofactor required for Tat activation of HIV-1 transcription; HIV TAT specific factor 1; HIV Tat-specific factor 1; RP1-196E23.2; Tat-SF1
基因别名: dJ196E23.2; HTATSF1; TAT-SF1; TATSF1
UniProt ID: (Human) O43719
Entrez Gene ID: (Human) 27336